Product Detail

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 HI024151 -----Isocorynoxeine

analytical standard     HPLC 98%

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Synonym:	Isocorynoxeine
Cas Number:	51014-29-0
Molecular Formula:	C22H26N2O4
Molecular Weight:	382.46

 




Chemical Name:	(16E,20a)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic  acid methyl ester
Appearance:	white  powder
Grade:	analytical standard
Assay:	=98%(HPLC)
Chemical Family:	Indole alkaloidscompounds
Original:	Uncaria rhynchophylla(Miq.)Jacks
Storage temp:	2~8°C
Pack Size:	20mg;100mg;1gram ;10gram;
Application:	For laboratory research use only




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Articles:

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1.Pharmacokinetic Study Of Isocorynoxeine Metabolites Mediated By Cytochrome P450 Enzymes In Rat And Human Liver Microsomes.

Zhao L, Zang B, Qi W, Chen F, Wang H, Kano Y, Yuan D.

PMID:

 

27094112

 


Abstract

Isocorynoxeine (ICN) is one of the major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla (Miq.) Jacks. that is widely used for the treatment of hypertension, vascular dementia, and stroke---Read More.




2.Metabolites of isocorynoxeine in rats after its oral administration.

Chen YP, Lu MN, Hao JC, Li MH, Hattori M, Wang W.

PMID:

 

25633191

 

Abstract

This work presents the metabolites of isocorynoxeine (ICOR), which is one of four bioactive tetracyclic oxindole alkaloids isolated from Uncaria hooks used commonly in the traditional Chinese medicines and Kampo medicine---Read More.