Product Detail

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 HC024149 -----Corynoxine B

analytical standard     HPLC 98%

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Synonym:	Corynoxine B
Cas Number:	17391-18-3
Molecular Formula:	C22H28N2O4
Molecular Weight:	384.47







Chemical Name:	methyl (Z)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
Appearance:	white  powder
Grade:	analytical standard
Assay:	=98%(HPLC)
Chemical Family:	Indole alkaloidscompounds
Original:	Uncaria rhynchophylla(Miq.)Jacks
Storage temp:	2~8°C
Pack Size:	20mg;100mg;1gram ;10gram;
Application:	For laboratory research use only

 





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Articles:

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1.HMGB1 Is Involved In Autophagy Inhibition Caused By SNCA/?-Synuclein Overexpression: A Process Modulated By The Natural Autophagy Inducer Corynoxine B.

Song JX, Lu JH, Liu LF, Chen LL, Durairajan SS, Yue Z, Zhang HQ, Li M.

PMID:

 

24178442

 

Abstract

SNCA/a-synuclein and its rare mutations are considered as the culprit proteins in Parkinson disease (PD). Wild-type (WT) SNCA has been shown to impair macroautophagy in mammalian cells and in transgenic mice---Read More.