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Gamabufotalin-465-11-2

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    If you are planning to wholesale gamabufotalin from one of the professional China gamabufotalin manufacturers and suppliers, please feel free to contact Baoji Herbest Bio-Tech Co.,Ltd.

    HG009072 -----Gamabufotalin

    analytical standard

     

    Synonym:Gamabufogenin; Gamabufagin; Gammabufotalin
    Cas Number:465-11-2
    Molecular Formula:C24H34O5
    Molecular Weight:402.52
    Chemical Name:3-beta,11-alpha,14-Trihydroxy-5-beta-bufa-20,22-dienolide
    Appearance:White powder
    Grade:analytical standard
    Assay:=98%(HPLC)
    Chemical Family: Bufadienolides compounds
    Original:Bufo bufo gargarizans Cantor
    Storage temp:2~8°C
    Pack Size:20mg; 100mg; 1gram ;10gram
    Application:For laboratory research use only

     

     

    Item and NamePack SizePrice(USD)Payment
    HG009072--Gamabufotalin20mg215.00PayPal
    HG009072--Gamabufotalin100mg635.00PayPal
    HG009072--Gamabufotalin500mg1220.00PayPal
    HG009072--Gamabufotalin1g1885.00PayPal


    Articles:

    1.Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer.

    Zhang L, Yu Z, Wang Y, Wang X, Zhang L, Wang C, Yue Q, Wang X, Deng S, Huo X, Tian X, Huang S, Zhang B, Ma X.

    PMID: 27384878

    Abstract

    Gamabufotalin (CS-6) is a major bufadienolide of Chansu, which shows desirable metabolic stability and less adverse effect in cancer therapy. CS-6 treatment inhibited the proliferation 

    of NSCLC in a nanomolar range. And CS-6 could induce G2/M cell cycle arrest and apoptosis in A549 cells. However, its ---Read More


    2.Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.

    Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC.

    PMID: 26657289

    Abstract

    Gamabufotalin (CS-6), a main active compound isolated from Chinese medicine Chansu, has been shown to strongly inhibit cancer cell growth and inflammatory response. However,

     its effects on angiogenesis have not been known yet. Here, we sought to determine the biological ---Read More 


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